Effect of Covid-19 Vaccines on Lactation

Joe Haydamous
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Abstract

Background: Pregnant and breastfeeding women were among the first to question the vaccine’s effects, especially on their lactating ability, given the fact these group of women were not included in the clinical trials of any vaccine. The confusion was exacerbated due to the fact that no study has clearly answered the question of safety of the vaccine on lactation. Methods: A complete literature search using seven databases including: PubMed, Academic Search Ultimate, AccessMedicine, AccessObGyn, Clinical Key, Medline, and ScienceDirect. Eligible studies published since March 11, 2020 till August 20, 2022 were considered Additionally, our paper aimed to tackle the effects on lactation upon administration of Covid-19 vaccines including but not limited to: Pfizer, Moderna, AstraZeneca, Sputnik, Johnson & Johnson, and Sinovac. The research conducted aimed to look over articles that showcase all the potential and possible complications that could have been the result of available Covid-19 vaccines at the time. Results and Discussion: After applying inclusion and exclusion criteria, and further reading and analysis across the listed databases, 29 articles were selected to proceed with this literature review. This literature review resulted in a paradox since many articles claim that vaccines have no adverse side effects on lactating women, while others argue the presence of some contradicting findings and effects that negatively impact lactation following administration of the Covid-19 vaccine. Conclusion: Further tailored and targeted studies that revolve around pregnant women, are needed to confirm current findings and dilemmas, using trusted rigorous methodologies.
Covid-19疫苗对泌乳的影响
背景:孕妇和哺乳期妇女是最早质疑疫苗效果的人群之一,特别是对她们的泌乳能力,因为这些妇女没有被包括在任何疫苗的临床试验中。由于没有研究明确回答疫苗对哺乳期的安全性问题,这种混乱加剧了。方法:使用PubMed、Academic search Ultimate、AccessMedicine、AccessObGyn、Clinical Key、Medline和ScienceDirect等7个数据库进行完整的文献检索。纳入自2020年3月11日至2022年8月20日期间发表的符合条件的研究。此外,我们的论文旨在研究接种Covid-19疫苗对泌乳的影响,包括但不限于:辉瑞、Moderna、阿斯利康、Sputnik、强生和科华。进行的这项研究旨在查看那些展示当时可用的Covid-19疫苗可能导致的所有潜在和可能的并发症的文章。结果和讨论:在应用纳入和排除标准,并对所列数据库进行进一步阅读和分析后,我们选择了29篇文章进行文献综述。这篇文献综述导致了一个悖论,因为许多文章声称疫苗对哺乳期妇女没有不良副作用,而另一些文章则认为存在一些相互矛盾的发现和影响,这些发现和影响在接种Covid-19疫苗后会对哺乳期产生负面影响。结论:需要进一步针对孕妇进行量身定制和有针对性的研究,以使用可靠的严格方法来确认当前的发现和困境。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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