https://researchopenworld.com/invited-commentary-proposing-potential-new-treatment-strategies-to-combat-breast-cancer-based-on-our-recently-published-manuscripts/#

Abstract

Most human breast cancers are hormone-dependent; as such they express estrogen and progesterone receptors (ER, PR). Such tumors respond more readily to chemotherapy than tumors that are hormone receptor negative. Women suffering from hormone receptor positive breast cancer are routinely treated with chemotherapeutic drugs such as tamoxifen and aromatase inhibitors, which either block the binding of estrogen to its receptor, or inhibit its synthesis.