Psidium guajava, Phalaenopsis sp., Syzygium aromaticum and Cinnamomum verum as natural inhibitors of growth of Streptococcus mutans

Letícia Maria Soares Azevedo, Camila Mara dos Reis, Marisa Cristina da Fonseca Casteluber
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引用次数: 1

Abstract

Currently, an increase on research on plant extracts seeking therapeutic action in the control of diseases of the oral cavity are observed, especially dental caries. Several plant extracts are already incorporated into toothpastes and mouthwashes. The objective of this study was to evaluate in vitro the antibacterial action of Psidium guajava (guava), Phalaenopsis sp. (orchid), Syzygium aromaticum (clove) and Cinnamomum verum (Ceylon cinnamon) extracts. The tests were carried out with the oral cavity bacterium Streptococcus mutans. The antibacterial activity of plant extracts was evaluated by the disk diffusion method in agar and by minimal inhibitory concentration (MIC). The tests showed the effectiveness of the extracts through inhibition zones of bacterial growth (from 5 to 20 mm in diameter) and MIC of 100 mg. mL-1 Phalaenopsis sp. extract and 50 mg. mL-1 P. guajava extract. Complementary studies will be needed to evaluate other pharmacological actions in order to use these plant extracts in different dental specialties and mainly in the treatment and prophylaxis of dental caries.
番石榴、蝴蝶兰、丁香和verum对变形链球菌生长的天然抑制作用
目前,植物提取物在口腔疾病,特别是龋齿的治疗作用方面的研究越来越多。一些植物提取物已经被添加到牙膏和漱口水中。研究了番石榴(Psidium guajava)、蝴蝶兰(Phalaenopsis sp.)、丁香(Syzygium aromaticum)和锡兰肉桂(Cinnamomum verum)提取物的体外抗菌作用。这些试验是用口腔细菌变形链球菌进行的。采用琼脂盘片扩散法和最低抑菌浓度法对植物提取物的抑菌活性进行了评价。试验表明,该提取物对细菌生长的抑制范围(直径5 ~ 20 mm)和MIC为100 mg。mL-1蝴蝶兰提取物和50 mg。mL-1瓜石榴提取物。为了将这些植物提取物用于不同的牙科专科,并主要用于龋齿的治疗和预防,还需要进行补充研究来评估其他药理作用。
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