Surgical Management of Ovarian Cancer

R. Bharathan
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Abstract

Advanced ovarian cancer remains a disease with a poor prognosis. Surgical therapy remains the cornerstone of treatment with essential contribution from chemotherapy. The combination therapy continues to offer the best treatment strategy. Complete cytoreductive surgery is still the most important prognostic marker. The role of primary debulking surgery in advanced ovarian cancer remains under investigation through high quality rigorous clinical trials. The current evidence regarding primary versus interval debulking surgery has drawn much criticism regarding patient recruitment and quality of surgery, both of which are key pillars in achieving complete cytoreduction. It is expected that greater centralisation and development of ‘ ovarian cancer surgery teams ’ will further enhance clinical outcomes.
卵巢癌的外科治疗
晚期卵巢癌仍然是一种预后不良的疾病。手术治疗仍然是治疗的基石,化疗的重要贡献。联合治疗仍然是最好的治疗策略。完全的细胞减少手术仍然是最重要的预后指标。通过高质量严格的临床试验,原发性减瘤手术在晚期卵巢癌中的作用仍在研究中。目前关于初次和间歇减体积手术的证据在患者招募和手术质量方面引起了许多批评,这两者都是实现完全细胞减少的关键支柱。预计“卵巢癌手术团队”的进一步集中和发展将进一步提高临床效果。
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