Investigation of the Amino Acid Composition of Tablets on the basis of Cryolophilized Xenoderm of Pigs

Abstract

The problem of creating highly effective drugs based on natural raw materials, especially of animal origin, is becoming increasingly relevant. Simultaneously with the search for effective ways to optimize the processes of reparative tissue regeneration, the issue of development of medicines based on animal raw materials with the possibility of correcting adverse for the organism of destructive immunopathological processes remains an important issue. The source of structural proteins with a wide range of biological activity is inherent in a bioorganic substrate based on the skin tissue of xenogeneic origin. The purpose of our work was to investigate the amino acid composition of the developed tablets based on the cryolophilized xenoderm pigs. Materials and Methods: Quantitative determination was carried out by ion exchange liquid chromatography. For qualitative and quantitative analysis of amino acids, the method of ion exchange liquid-column chromatography (the principle of action is based on the acid-alkaline properties of these compounds) and the automatic analyzer 339 M of the firm “Microtechna” (Czech Republic) Conclusion: The analysis of pills based on cryolophilized xenoderm of pigs with lecithin on the content of amino acids in the investigated objects was performed. As a result of the research, 19 amino acids were identified, 12 of which are irreplaceable.