Cardioprotective effect of pulicaria wightania against isoproterenol induced myocardial infarction in experimental rats

C. Sumanjali, R. Manohar, S. Sheeba, M. Syamala, T. Jyothsana
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Abstract

The current study was carried out to evaluate the cardio protective activity of Pulicaria Wightiana against Isoproterenol (ISO) induced myocardial infarction (MI). Pretreatment to the different groups were given for 30 days and ISO was administered at last two days with an interval of 24 hrs. Due to chronic ionotropy ISO induces MI. Blood was collected at the last day of experimental period and biomarkers were observed. The results indicate that the extract exhibited significant cardioprotective activity.
白芍对异丙肾上腺素所致大鼠心肌梗死的心脏保护作用
本研究旨在评价白芍对异丙肾上腺素(ISO)诱发的心肌梗死(MI)的心脏保护作用。各组预处理30 d,最后2 d给予ISO,间隔24 h。由于慢性电离性ISO诱导心肌梗死,在实验最后一天采集血液并观察生物标志物。结果表明,该提取物具有明显的心脏保护作用。
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