From rags to riches

Abstract

lating effects via PDGF receptors that are expressed in many types of tumor cells, and these effects may account for increased propensity for metastasis. As the 2 current HGF studies show, many of the factors that stimulate lymphangiogenesis could be context dependent in their mechanisms of action. The contribution of their indirect effects on lymphangiogenesis via stromal cells, leukocytes, and the inflammatory response should therefore be carefully analyzed. ■