Myeloid Sarcoma Presenting with Quadriparesis: A Difficult Journey through COVID Times—Lessons Learned

Abstract

A 16-year-old girl presented with acute-onset quadriparesis with urinary incontinence. Examination revealed an upper motor neuron (UMN) pattern of weakness in all four limbs, accompanied by a UMN type of bladder involvement in a shock stage. Two significant cervical lymph nodes were noted in the right submandibular region. MRI of the cervical spine revealed an extradural mass, compressing the cord at the C2 to C4 region. Excisional biopsy of the cervical lymph nodes revealed an extramedullary myeloid sarcoma, and immunohistochemistry showed CD117 and myeloperoxidase positivity.