A 2D model of traveling wave Dielectrophoresis microelectrode array based on printed circuit board technology for manipulation and characterization of malignant and normal liver cells

2016 Fourth International Japan-Egypt Conference on Electronics, Communications and Computers (JEC-ECC) Pub Date : 2016-05-01 DOI:10.1109/JEC-ECC.2016.7518975

Reda Abdelbaset, Y. Ghallab, Hamdy Abdelhamid, Y. Ismail, M. El-Wakad

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引用次数: 2

Abstract

the Dielectrophoresis (DEP) is a phenomenon in which a force exists on a particle due to a non-uniform electric field. A widely used technique for particle manipulation and separation is a traveling wave dielectrophoresis (twDEP), where it is particularly applied to biological particles. In this work, a 2D model of traveling wave microelectrode array of printed circuit board (PCB) based technology is presented and discussed. The twDEP is an electro-kinetic technique resulting from the interaction of a non-uniform electric field and polarizable particles. The electric field and the interaction of a nonuniform electric field and polarizable particles were simulated using COMSOL Multiphysics®. The proposed twDEP is used to manipulate liver cells and distinguish between malignant and normal liver cells. In the scope of paper, a concentric ring microelectrodes based on PCB technology are designed for manipulating liver cells, as well distinguishing between malignant and normal liver cells using COMSOL Multiphysics®.

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基于印刷电路板技术的行波双向电泳微电极阵列二维模型，用于恶性和正常肝细胞的操作和表征

Dielectrophoresis (DEP)是指由于非均匀电场作用在粒子上的力。行波介质电泳(twDEP)是一种广泛应用于颗粒操作和分离的技术，尤其适用于生物颗粒。本文提出并讨论了基于印刷电路板(PCB)技术的行波微电极阵列二维模型。twDEP是一种由非均匀电场和极化粒子相互作用产生的电动力学技术。利用COMSOL Multiphysics®模拟了非均匀电场和极化粒子的相互作用。所提出的twDEP用于操纵肝细胞并区分恶性和正常肝细胞。在本文的范围内，基于PCB技术的同心环微电极被设计用于操纵肝细胞，以及使用COMSOL Multiphysics®区分恶性和正常肝细胞。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

2016 Fourth International Japan-Egypt Conference on Electronics, Communications and Computers (JEC-ECC)

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