Non-Surgical management with Intra-Arterial Concurrent Chemo Radio Therapy (IACCRT) can be a definitive organ preservation treatment for buccal cancer patient

Young Andrew Yau-Wah, Yen Cheng-Yo, Hung Chil-Hsin
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Abstract

Conventional Head and Neck cancer treatment with primary surgical intervention is a relatively suffering manipulation because of causing severe facial deformity, and mastication malfunction, and resulted in a very poor quality of life for the patients afterward. And post-operation adjuvant therapy with combined modality treatment with Concurrent Chemo-Radio Therapy (CCRT) has been recommended approach for H&N cancer for decades too. But it is also relatively more toxic to the patient, and further severely disrupts patients’ quality of life due to systemic side-effects caused by intravenous cytotoxic drug delivery. Intra-arterial infusion chemotherapy is another option for CCRT because of not only a better tumor response documented, and also bonus a better quality of life improvement. The demonstrated H&N cancer patient approaching with Intra-Arterial Concurrent Chemo-Radio Therapy (IACCRT) showed a very satisfactory curative outcome. Besides the much better quality of life for the patient was conserved, it also bonuses to restore the patient’s dignity of life when compared to the conventional suffering surgical intervention. Such highly humanize IACCRT treatment modality for H&N cancer patients should be recommended and encouraged in clinical practice.
动脉内同步放化疗(IACCRT)的非手术治疗可以成为口腔癌患者器官保存的最终治疗方法
常规头颈癌的手术治疗是一种相对痛苦的操作,因为会导致严重的面部畸形和咀嚼功能障碍,导致患者术后的生活质量很差。而术后辅助治疗与同步放化疗(CCRT)联合治疗也被推荐为治疗H&N癌的方法。但它对患者的毒性也相对更大,并且由于静脉细胞毒性药物给药引起的全身副作用,进一步严重扰乱患者的生活质量。动脉内输注化疗是CCRT的另一种选择,因为不仅有更好的肿瘤反应记录,而且还能提高生活质量。经证实的H&N癌患者接受动脉内同步放化疗(IACCRT)治疗,取得了非常满意的疗效。除了保留了患者更好的生活质量外,与传统的手术干预相比,它还有助于恢复患者的生命尊严。这种高度人性化的IACCRT治疗H&N癌的方式在临床实践中值得推荐和鼓励。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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