Comparison of Efficacy of Diclofenac versus Aceclofenac in Post Operative Pain in Lower limb fractures: a Double blind, Randomized Study

Abstract

INTRODUCTION: Providing effective postoperative analgesia is a significant challenge in patients undergoing orthopedic surgery. Non steroidal anti-inflammatory group of drugs is used mostly to achieve it. This clinical study was done to investigate efficacy of Injectable Aceclofenac over inj. Diclofenac in patients with severe postoperative pain in lower limb fractures. METHODS: 100 patients (aged 18-60 yr) of lower limb fractures were enrolled as per inclusion criteria . They were randomly assigned to Group A or Group B (50 patients each ) .Severe pain was postoperative pain 7 or >7 on Numerical Rating Scale. For postoperative analgesia, in Group A Inj. Aceclofenac ( 12 hourly) and in Group B Inj. Diclofenac (8 hourly) was given . To abort pain in case of no relief Inj. Tramadol was given. Decrease in Numerical Rating Scale score in either the group and