Effects of Light Waveforms on a Circadian Oscillation of Clock Genes

K. Tsumoto, G. Kurosawa, K. Aihara
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Abstract

For studying autonomous circadian rhythms of proteins in organisms, various mathematical models have been proposed. In this study, we have investigated bifurcations of periodic oscillations observed in circadian models incorporating the effect on a light-dark cycle and show that the waveform of the periodic variation in the light-induced parameter has a marked influence on the global bifurcation structure or the type of dynamic behavior resulting from the forcing term of the circadian oscillator by the LD cycles
光波形对时钟基因昼夜节律振荡的影响
为了研究生物体内蛋白质的自主昼夜节律,人们提出了各种各样的数学模型。在这项研究中,我们研究了在昼夜节律模型中观察到的周期振荡的分岔,并结合了对光-暗周期的影响,并表明光诱导参数的周期变化波形对昼夜节律振荡器由LD周期强制项引起的全局分岔结构或动态行为类型有显著影响
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