Rune Wilkens – Joint Winner Young Investigator Award Euroson 2015

Abstract

Study aims: 1. Repeatability assessment for dynamic CEUS parameters measured within the thickened bowel wall of patients with active CD. 2. Comparison of these initial time intensity curve parameters with dynamic contrast enhanced MR enterography (DCE-MRE). Methods ▼ 25 patients with moderate to severe CD underwent both DCE-MRE and CEUS within a week. SonoVue (2x2.4 ml) was injected before axial and longitudinal scans of the most inflamed bowel segment. CEUS was quantified with “Vuebox” (Bracco). Up to 4 regions of interests were drawn with size >0.1 cm2. DCE-MRE using Gadolinium in a dynamic T1-sequence (VIBE), was analyzed using an in-house developed program. CEUS intensity data were log-converted before analysis and regression analysis and limits of agreement (LoA) were computed.