{"title":"Early versus Late Initiation of Dialysis","authors":"M. Hochman","doi":"10.1093/med/9780199343560.003.0019","DOIUrl":null,"url":null,"abstract":"This chapter provides a summary of a landmark study in internal medicine. Can the initiation of dialysis safely be delayed in patients with an estimated glomerular filtration rate (GFR) ≤14.0 mL per minute who do not demonstrate traditional signs or symptoms indicating the need for dialysis? Starting with that question, it describes the basics of the study, including funding, study location, who was studied, how many patients, study overview, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.","PeriodicalId":243490,"journal":{"name":"50 Studies Every Doctor Should Know","volume":"164 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2013-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"50 Studies Every Doctor Should Know","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/med/9780199343560.003.0019","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
This chapter provides a summary of a landmark study in internal medicine. Can the initiation of dialysis safely be delayed in patients with an estimated glomerular filtration rate (GFR) ≤14.0 mL per minute who do not demonstrate traditional signs or symptoms indicating the need for dialysis? Starting with that question, it describes the basics of the study, including funding, study location, who was studied, how many patients, study overview, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.
本章概述了一项具有里程碑意义的内科学研究。对于估计肾小球滤过率(GFR)≤14.0 mL /分钟且没有显示需要透析的传统体征或症状的患者,是否可以安全地延迟开始透析?从这个问题开始,它描述了研究的基本内容,包括资金、研究地点、研究对象、患者人数、研究概述、研究干预、随访、终点、结果、批评和局限性。本章简要回顾了其他相关的研究和信息,讨论了影响,并以一个相关的临床病例结束。