Rat endo- and mesothelium lack Fc receptors

Abstract

The present study is concerned with the interaction of rat endo- and mesothelium with homologous erythrocytes under various conditions of pretreatment and incubation. Its findings show rat endo- and mesothelial cells

• a)

  nonadhesive to native or pretreated erythrocytes irrespective of the presence of gamma-globulin in the medium,

• b)

  devoid of primary or cryptic receptors sensitive to the Fc segment of the IgG molecule, and

• c)

  provided with binding sites at the oxidized glycocalyx which together with receptor groups of modified erythrocytes share the same class of IgG.