Why Is COVID-19 Mortality in Lombardy so High? Evidence from the Simulation of a SEIHCR Model

Carlo A. Favero
{"title":"Why Is COVID-19 Mortality in Lombardy so High? Evidence from the Simulation of a SEIHCR Model","authors":"Carlo A. Favero","doi":"10.2139/ssrn.3566865","DOIUrl":null,"url":null,"abstract":"The standard SEIR model based on a parameterization consistent with the international evidence cannot explain the very high COVID-19 related mortality in Lombardy. This paper proposes an extension of the standard SEIR model that is capable of solving the puzzle. The SEIR model features exogenous mortality: once Susceptible individuals become first Exposed, and then Infected, they succumb with a given probability. The extended model inlcudes an Hospitlization process and the possibility that Hospitalized patients, who need to resort to Intensive Care Unit, cannot find availability because the ICU is saturated. This Constraint creates an additional increase in mortality, which is endogenous to the diffusion of the disease. The SEIHCR (H stands for Hospitalization and C stands for Constraint) is capable of explaining the dynamics of COVID-19 related mortality in Lombardy with a paramerization consistent with the international evidence.","PeriodicalId":132014,"journal":{"name":"MedRN: Respiratory Tract Infections (Topic)","volume":"45 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2020-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"18","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"MedRN: Respiratory Tract Infections (Topic)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2139/ssrn.3566865","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 18

Abstract

The standard SEIR model based on a parameterization consistent with the international evidence cannot explain the very high COVID-19 related mortality in Lombardy. This paper proposes an extension of the standard SEIR model that is capable of solving the puzzle. The SEIR model features exogenous mortality: once Susceptible individuals become first Exposed, and then Infected, they succumb with a given probability. The extended model inlcudes an Hospitlization process and the possibility that Hospitalized patients, who need to resort to Intensive Care Unit, cannot find availability because the ICU is saturated. This Constraint creates an additional increase in mortality, which is endogenous to the diffusion of the disease. The SEIHCR (H stands for Hospitalization and C stands for Constraint) is capable of explaining the dynamics of COVID-19 related mortality in Lombardy with a paramerization consistent with the international evidence.
为什么伦巴第省COVID-19死亡率如此之高?SEIHCR模式模拟的证据
基于与国际证据一致的参数化的标准SEIR模型无法解释伦巴第省与COVID-19相关的极高死亡率。本文提出了一个标准SEIR模型的扩展,能够解决这个难题。SEIR模型的特点是外源性死亡率:一旦易感个体首先暴露,然后被感染,他们就会以给定的概率死亡。扩展模型包括住院过程,以及住院患者由于ICU已饱和而无法求助于重症监护室的可能性。这种限制造成了死亡率的额外增加,这是疾病扩散的内生因素。SEIHCR (H代表住院治疗,C代表约束)能够以与国际证据一致的参数化方式解释伦巴第省与COVID-19相关的死亡率动态。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信