RESULTS OF AN ELECTROCARDIOGRAPHIC STUDY IN HCM IN CATS OF DIFFERENT AGES

Korobova V.V.
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Abstract

Cardiomyopathies are a heterogeneous group of myocardial diseases with varying phenotypes and prognosis. Feline cardiomyopathies are common, and cardiovascular disease is among the 10 most common causes of death in cats. Hypertrophic cardiomyopathy (HCM) is a common cause of heart failure, arterial thromboembolism, and sudden death in cats. HCM is a primary myocardial lesion characterized by unexplained left ventricular hypertrophy (LVH) and impaired myocardial relaxation. The cause of primary or idiopathic in cats is unknown, but hereditary pathology probably exists in many cases. The disease is widespread in breeds such as Maine Coon, Persian, Ragdoll, American Shorthair. There are also reports of HCM in littermates and other close relatives of domestic shorthair cats. The method of electrocardiography is quite sensitive in the diagnosis of cardiomyopathies in humans, therefore, the study of ECG signs of HCM in cats, as well as the study of the dynamics of disease progression, the development and improvement of the treatment of this disease is an urgent scientific and practical problem in veterinary medicine, which has not been sufficiently resolved to date. According to the obtained ECG data, it can be concluded that recording in animals of different ages, as well as in animals that have a hereditary predisposition to the development of this disease, can play a key role in diagnosing an early stage of cardiomyopathy. The prevalence of HCM in cats with a predisposition to this disease is much higher than in cats without this genetic predisposition. Further studies involving more cats with HCM, secondary left ventricular hypertrophy, and normal hearts are proposed to better understand the heterogeneity and complexity of this myocardial disease.
不同年龄猫HCM的心电图研究结果
心肌病是一组异质性心肌疾病,具有不同的表型和预后。猫的心肌病很常见,心血管疾病是猫十大最常见的死亡原因之一。肥厚性心肌病(HCM)是猫心衰、动脉血栓栓塞和猝死的常见原因。HCM是一种原发心肌病变,其特征是无法解释的左心室肥厚(LVH)和心肌舒张受损。猫的原发或特发性原因尚不清楚,但在许多情况下可能存在遗传病理。这种疾病在缅因库恩、波斯、布娃娃、美国短毛等品种中广泛存在。也有报道称,家短毛猫的幼崽和其他近亲也有HCM。心电图方法在人类心肌病的诊断中是相当敏感的,因此,研究猫HCM的心电图征象,以及研究疾病进展的动力学,开发和改进这种疾病的治疗方法是兽医学中迫切需要解决的科学和现实问题,迄今尚未得到充分解决。根据所获得的心电图数据,可以得出结论,记录不同年龄的动物,以及对该疾病的发展具有遗传易感性的动物,可以在早期诊断心肌病中发挥关键作用。有这种疾病易感性的猫的HCM患病率远高于没有这种遗传易感性的猫。为了更好地了解这种心肌疾病的异质性和复杂性,我们建议对更多患有HCM、继发性左心室肥厚和正常心脏的猫进行进一步的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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