Fluorescent and photodynamic properties of near-infrared photosensitizer bacteriochlorophyllide-serine

Current Research on Laser Use in Oncology Pub Date : 2005-08-08 DOI:10.1117/12.640051

I. Meerovich, I. Kubasova, N. Oborotova, G. Meerovich, S. Demura, A. Brandis, V. Rosenbach‐Belkin, A. Baryshnikov, A. Scherz

引用次数: 1

Abstract

Study is devoted to investigation of fluorescent and photodynamic properties of near-infrared photosensitizer bacteriochloriphyllide-serine. The peculiarities of its fluorescence excited by different lasers, dynamics and selectivity of accumulation were investigated. Photodynamic therapy of mice and investigation of tissue de-oxygenation during tumor irradiation were performed. It was shown that bacteriochloriphyllide-serine is an effective photosensitizer for PDT and fluorescent diagnostics of tumors.

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近红外光敏剂细菌叶绿素丝氨酸的荧光和光动力学性质

研究了近红外光敏剂细菌氯叶碱丝氨酸的荧光和光动力学特性。研究了其荧光在不同激光激发下的特性、积累动力学和选择性。对小鼠进行了光动力治疗，并对肿瘤照射过程中组织脱氧情况进行了研究。结果表明，细菌氯叶磷脂丝氨酸是一种有效的光敏剂，用于肿瘤的PDT和荧光诊断。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Research on Laser Use in Oncology

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