Silicon Photonics System for Low-Cost Rapid Quantification of Biomarkers in Blood

Abstract

We introduce a low-cost swept-source optical reader and disposable microfluidic cartridge system for multiplexed point-of-care and at-home diagnostics using photonic microresonators. In a triple-blind study of high-sensitivity C-Reactive Protein (hsCRP) quantification in blood plasma, our system demonstrated good agreement (R>0.9) with gold-standard lab measurement techniques.