[Participation of some nucleotides in regulation of phosphoprotein phosphates activity in rat and chicken myocardium].

Abstract

Adenine- and uridine di- and triphosphates (in a 3 mM concentration) increase considerably phosphoprotein phosphatase (PPPase) (EC 3.1.3.16) activity of rat and chicken myocardium homogenates. AMP and Pi are effective inhibitors of the enzyme. The ATP activating effect is also shown in partially purified preparations of rat myocardium PPPase. ATP is able of protecting significantly the enzyme during its thermodenaturation.