Determination of the gain of the baroreceptive mechanisms on heart rate and arterial pressure variability signals

[1989] Proceedings. Computers in Cardiology Pub Date : 1989-09-19 DOI:10.1109/CIC.1989.130469

S. Cerutti, G. Baselli, L. Biancardi, R. Furlan, Alberto Mailliani, M. Pagani, A. Porta, O. Rimoldi

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引用次数: 2

Abstract

The performance of baroreceptive mechanisms is classically evaluated by measuring the lengthening of the heart period (HP) in response to a symbolic arterial pressure (SAP) rise. The authors present several methods for calculating the gain of the SAP-HP relationship through proper processing of cardiovascular variability signals. The spectral analysis of such signals makes it possible to enhance some parameters which satisfactorily describe the level of control elicited by the sympathovagal balance on cardiovascular functions. The advantages of this approach compared with the classical one, which uses an injection of i.v. vasoconstrictor drug as the input stimulation, are twofold. First, it is possible to measure alpha parameters in the patient even for long periods of recordings (up to 24 h or more) without using drugs which produce a change in the physiological short-term steady-state condition. Secondly, it is possible to use the parameters of cardiovascular variability signals for the design and validation of proper 'black-box' physiological modeling.<>

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心率和动脉压变异性信号的压力感受机制增益的测定

压力感受机制的性能通常是通过测量响应象征性动脉压(SAP)升高的心脏周期延长(HP)来评估的。作者提出了几种通过适当处理心血管变异性信号来计算SAP-HP关系增益的方法。这些信号的频谱分析可以提高一些参数，这些参数令人满意地描述了交感迷走神经平衡对心血管功能的控制水平。与使用静脉注射血管收缩药物作为输入刺激的传统方法相比，这种方法的优点是双重的。首先，即使是长时间的记录(长达24小时或更长时间)，也可以测量患者的α参数，而无需使用药物来产生生理短期稳态条件的变化。其次，有可能使用心血管变异性信号的参数来设计和验证适当的“黑盒”生理模型。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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[1989] Proceedings. Computers in Cardiology

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