The Clinical Impact of Myocardial Perfusion Scintigraphy in the Evaluation of Coronary Artery Disease in 2009

C. Pirich, T. Seifen, P. Keinrath, L. Rettenbacher
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Abstract

Myocardial perfusion imaging (MPI) using single photon emission computed tomography (SPECT) or positron emission tomography (PET) techniques is a well-established diagnostic tool in clinical medicine providing non-invasively information about cardiac perfusion, function and prognosis in patients with coronary artery disease. Gated SPECT MPI has been used in clinical routine for years allowing the characterization of localization, extent and severity of perfusion abnormalities both in women and men. Recently, clinical studies employing nuclear techniques (e.g. BASKET or COURAGE) have underlined its diagnostic accuracy, prognostic validity and its importance for the clinical decision making. The extent of stress-induced ischaemia is of clinical relevance to guide decision making in the management of the cardiac patient. Improvements in nuclear imaging equipment, software for image analysis and stress techniques will accelerate the procedure and increase its diagnostic accuracy while reducing radiation exposure.

2009年心肌灌注显像评价冠状动脉病变的临床意义
使用单光子发射计算机断层扫描(SPECT)或正电子发射断层扫描(PET)技术的心肌灌注成像(MPI)是临床医学中公认的诊断工具,为冠状动脉疾病患者提供心脏灌注、功能和预后的无创信息。门控SPECT MPI已经在临床常规中使用多年,可以对女性和男性灌注异常的定位、程度和严重程度进行表征。近年来,应用核技术(如BASKET或COURAGE)的临床研究强调了其诊断准确性、预后有效性及其对临床决策的重要性。应激性缺血的程度对指导心脏病患者的治疗决策具有临床意义。核成像设备、图像分析软件和应力技术的改进将加速这一过程,提高诊断准确性,同时减少辐射暴露。
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