Multidrug resistant enterohaemorrhagic Escherichia coli serogroups in the faeces of hunted Wildlife, Abeokuta, Nigeria.

IF 0.5 4区农林科学 Q4 VETERINARY SCIENCES

Veterinaria italiana Pub Date : 2022-12-30 DOI:10.12834/VetIt.1990.12087.2

Olufemi Ernest Ojo, Elizabeth Adesola Amosun, Oluwadaisi Oluwaseyi Opebiyi, Mufutau Atanda Oyekunle, Morenike Atinuke Dipeolu, Ebenezer Babatunde Otesile

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引用次数: 0

Abstract

Wildlife play significant roles in the dissemination and zoonotic transmission of pathogens. The enterohaemorrhagic Escherichia coli (EHEC) are associated with complicated cases of food-borne illnesses. This study investigated the presence of EHEC serogroups (O26, O45, O103, O145, O91, O111, O128, O121 and O157) in wildlife species: cane rats (Thryonomys swinderianus), royal antelope (Neotragus pygmaeus), African giant rats (Cricetomys gambianus) and waterbuck (Kobus ellipsiprymnus). EHEC and non-EHEC isolates from these wildlife sources were tested for susceptibility to antimicrobial agents. Overall, 127 (83.0 %) of 153 samples yielded E. coli. Nine (5.9%) samples were positive for EHEC belonging to three serogroups as follows; O26 (n=2), O111 (n=2) and O103 (n=5). The EHEC isolates were from cane rats (n=6) and royal antelope (n=3) and possessed virulence-associated genes stx1 (77.8%), stx2 (100.0%), eaeA (100.0%) and hlyA (100.0%). Overall, 127 E. coli isolates showed resistance to ampicillin (99.2%), ceftiofur (90.6%), tetracycline (90.0%), cephalexin (87.4%), cefotaxime (50.4%), streptomycin 42.5%, ceftazidime (41.7%), nalidixic acid (37.0%), ciprofloxacin (43.6%), amoxicillin/clavulanic acid (32.3%), gentamicin (27.6%), sulphamethoxazole/trimethoprim (25.2%), norfloxacin (17.3%) and chloramphenicol (11.0%). The roles of wildlife in the dissemination and transmission of antimicrobial resistant and zoonotic bacteria should not be neglected for effective preventive and control strategies.

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尼日利亚阿贝奥库塔被猎杀野生动物粪便中的多重耐药肠出血性大肠杆菌血清群。

野生动物在病原体的传播和人畜共患传播中起着重要作用。肠出血性大肠杆菌(EHEC)与食源性疾病的复杂病例有关。本研究调查了O26、O45、O103、O145、O91、O111、O128、O121和O157在甘蔗大鼠(Thryonomys swinderianus)、皇家羚羊(Neotragus pygmaeus)、非洲巨鼠(Cricetomys gambianus)和羚羊(Kobus ellipsiprymnus)等野生动物中的存在情况。对来自这些野生动物来源的肠出血性大肠杆菌和非肠出血性大肠杆菌分离株进行了抗菌药物敏感性测试。总体而言，153份样品中有127份(83.0%)检出大肠杆菌。9份(5.9%)样品呈肠出血性大肠杆菌阳性，分别属于以下3个血清组;O26 (n=2)， O111 (n=2)， O103 (n=5)。从甘蔗大鼠(n=6)和羚羊(n=3)分离出EHEC，具有毒力相关基因stx1(77.8%)、stx2(100.0%)、eaeA(100.0%)和hlyA(100.0%)。总体而言，127株大肠杆菌对氨苄西林(99.2%)、头孢替弗(90.6%)、四环素(90.0%)、头孢氨苄(87.4%)、头孢噻肟(50.4%)、链霉素(42.5%)、头孢他啶(41.7%)、萘啶酸(37.0%)、环丙沙星(43.6%)、阿莫西林/克拉维酸(32.3%)、庆大霉素(27.6%)、磺胺甲恶唑/甲氧苄啶(25.2%)、诺氟沙星(17.3%)和氯霉素(11.0%)耐药。野生动物在抗微生物药物耐药性和人畜共患细菌的传播和传播中的作用不应被忽视，以制定有效的预防和控制战略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Veterinaria italiana VETERINARY SCIENCES-

CiteScore

1.50

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The journal was created as the Croce Azzurra in 1950. A quarterly peer-reviewed journal devoted to veterinary public health and other aspects of veterinary science and medicine, Veterinaria Italiana is published by the Istituto Zooprofilattico Sperimentale dell’Abruzzo e del Molise ‘G. Caporale’ (Istituto Zooprofilattico Sperimentale dell''Abruzzo e del Molise) in Teramo, Italy. The goal of the journal is to provide an international platform for veterinary public health information from Italy and other countries, particularly those in Eastern Europe and Africa, Asia and South America. Veterinarians and veterinary public health specialists are encouraged to share their knowledge and experience on this platform.