Age-specific effect of transurethral holmium laser enucleation of the prostate on overactive bladder in men with benign prostatic hyperplasia: An investigation using an overactive bladder symptom score

IF 1.5 4区医学 Q3 UROLOGY & NEPHROLOGY

LUTS: Lower Urinary Tract Symptoms Pub Date : 2022-12-11 DOI:10.1111/luts.12469

Yasuharu Takeuchi, Yoshitomo Sawada, Shoutarou Watanabe, Yasuo Ni-itsu, Noritoshi Sekido

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引用次数: 1

Abstract

Objectives

To investigate the age-specific effect of transurethral holmium laser enucleation of the prostate (HoLEP) on overactive bladder (OAB).

Methods

A total of 186 consecutive patients who underwent HoLEP were included. They were divided into three groups: patients aged less than 65 years, between 65 and 74, and 75 or older. The OAB symptom score as well as other relevant variables of lower urinary tract symptoms and function were assessed before and 1, 3, 6, and 12 months after surgery. Age-specific prevalence of OAB, the proportion of resolution of OAB, and de novo OAB were evaluated.

Results

The mean age of patients was 70.7 years, and the mean total prostate volume was 75.8 ml. The mean OAB symptom scores before surgery of patients aged less than 65 years, between 65 and 74, and 75 or older were 6.0, 5.2, and 5.7, respectively. At 12 months after surgery, the scores for the respective groups had significantly decreased to 2.1, 2.5, and 3.5. The prevalence of OAB based on the score in the respective groups was 45.8%, 56.9%, and 54.0% (p = .6391) preoperatively and 9.1%, 11.3%, and 15.8% at 12 months after the surgery (p = .7613). Of those with preoperative OAB, 75.0%, 79.2%, and 75.0% of the respective groups showed resolution of OAB at 12 months postoperatively (p = .9427).

Conclusions

In candidates for surgical deobstruction of benign prostatic hyperplasia, HoLEP has potential to improve OAB symptoms regardless of age.

查看原文本刊更多论文

经尿道钬激光前列腺摘除对良性前列腺增生患者膀胱过动症的年龄特异性影响:一项使用膀胱过动症症状评分的研究

目的探讨经尿道钬激光前列腺剜除术（HoLEP）治疗膀胱过度活动症（OAB）的年龄特异性效果。方法纳入186例连续接受HoLEP的患者。他们被分为三组：年龄小于65岁的患者年龄在65岁至74岁之间，75岁或以上。OAB症状评分以及下尿路症状和功能的其他相关变量在1、3、6和12之前进行了评估手术后数月。评估了OAB的年龄特异性患病率、OAB消退的比例和新发OAB。结果患者平均年龄70.7岁年，平均前列腺总体积为75.8 ml年龄小于65岁的患者手术前OAB症状评分的平均值年龄分别为6.0、5.2和5.7岁，年龄在65岁至74岁之间，年龄在75岁或以上。在12 术后数月，各组的评分分别降至2.1、2.5和3.5。根据各组的评分，OAB的患病率分别为45.8%、56.9%和54.0%（p= .6391），术前和术后分别为9.1%、11.3%和15.8% 术后数月（p= .7613）。在术前OAB患者中，分别有75.0%、79.2%和75.0%的患者在12 术后数月（p= .9427）。结论无论年龄大小，HoLEP都有可能改善前列腺增生症的OAB症状。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

LUTS: Lower Urinary Tract Symptoms UROLOGY & NEPHROLOGY-

CiteScore

3.00

自引率

7.70%

发文量

审稿时长

>12 weeks

期刊介绍： LUTS is designed for the timely communication of peer-reviewed studies which provides new clinical and basic science information to physicians and researchers in the field of neurourology, urodynamics and urogynecology. Contributions are reviewed and selected by a group of distinguished referees from around the world, some of whom constitute the journal''s Editorial Board. The journal covers both basic and clinical research on lower urinary tract dysfunctions (LUTD), such as overactive bladder (OAB), detrusor underactivity, benign prostatic hyperplasia (BPH), bladder outlet obstruction (BOO), urinary incontinence, pelvic organ prolapse (POP), painful bladder syndrome (PBS), as well as on other relevant conditions. Case reports are published only if new findings are provided. LUTS is an official journal of the Japanese Continence Society, the Korean Continence Society, and the Taiwanese Continence Society. Submission of papers from all countries are welcome. LUTS has been accepted into Science Citation Index Expanded (SCIE) with a 2011 Impact Factor.