Organization of Chromosomal DNA by SMC Complexes.

IF 8.7 1区生物学 Q1 GENETICS & HEREDITY

Annual review of genetics Pub Date : 2019-12-03 Epub Date: 2019-10-02 DOI:10.1146/annurev-genet-112618-043633

Stanislau Yatskevich, James Rhodes, Kim Nasmyth

引用次数: 0

Abstract

Structural maintenance of chromosomes (SMC) complexes are key organizers of chromosome architecture in all kingdoms of life. Despite seemingly divergent functions, such as chromosome segregation, chromosome maintenance, sister chromatid cohesion, and mitotic chromosome compaction, it appears that these complexes function via highly conserved mechanisms and that they represent a novel class of DNA translocases.

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SMC 复合物对染色体 DNA 的组织作用

染色体结构维持（SMC）复合体是所有生命体染色体结构的关键组织者。尽管染色体分离、染色体维持、姐妹染色单体内聚和有丝分裂染色体压实等功能看似各不相同，但这些复合体似乎是通过高度保守的机制发挥作用的，它们代表了一类新型 DNA 易位酶。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annual review of genetics 生物-遗传学

CiteScore

18.30

自引率

0.90%

发文量

期刊介绍： The Annual Review of Genetics, published since 1967, comprehensively covers significant advancements in genetics. It encompasses various areas such as biochemical, behavioral, cell, and developmental genetics, evolutionary and population genetics, chromosome structure and transmission, gene function and expression, mutation and repair, genomics, immunogenetics, and other topics related to the genetics of viruses, bacteria, fungi, plants, animals, and humans.