How can we improve response assessments in MDS? Strategies to improve response assessment in MDS treatment paradigms

IF 2.2 4区医学 Q3 HEMATOLOGY

Best Practice & Research Clinical Haematology Pub Date : 2022-12-01 DOI:10.1016/j.beha.2022.101405

Rafael Bejar

引用次数: 2

Abstract

Evaluating response to treatment in MDS represents a major challenge due to its associated complexity and heterogeneity. Although response criteria have been proposed by the IWG and revised on several occasions, these criteria have limitations. This review has outlined some refinements that can be used to improve response assessment and to ensure the identification of clinically meaningful endpoints.

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我们如何改进MDS的疗效评估?改善MDS治疗模式疗效评估的策略

由于其相关的复杂性和异质性，评估MDS治疗的反应是一个主要的挑战。虽然工作组提出了反应标准，并进行了多次修订，但这些标准都有局限性。本综述概述了一些可用于改善疗效评估和确保确定临床有意义的终点的改进方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Best Practice & Research Clinical Haematology 医学-血液学

CiteScore

4.20

自引率

0.00%

发文量

审稿时长

35 days

期刊介绍： Best Practice & Research Clinical Haematology publishes review articles integrating the results from the latest original research articles into practical, evidence-based review articles. These articles seek to address the key clinical issues of diagnosis, treatment and patient management. Each issue follows a problem-orientated approach which focuses on the key questions to be addressed, clearly defining what is known and not known, covering the spectrum of clinical and laboratory haematological practice and research. Although most reviews are invited, the Editor welcomes suggestions from potential authors.