Synthesis of β-Hydroxysulfides via Multi-Component Cascade Hydroxysulfenylation of Styrenes with NH4SCN and Water under Transition-metal-free Conditions

IF 3.5 3区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemistry - An Asian Journal Pub Date : 2023-11-14 DOI:10.1002/asia.202300901

Xian Liu, Liqiang Hao, Yangyang Wang, Yafei Ji

引用次数: 0

Abstract

Transition-mental-free multi-component hydroxysulfenylation of styrenes with NH₄SCN and water to from β-hydroxysulfides is established. The reaction mechanism proceeded via a domino reaction after a radical addition to 2-phenylimidazo[1,2-a]pyridines. This approach features a wide substrate scope and functional group compatibility, providing 34 compounds in acceptable yields.

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无过渡金属条件下苯乙烯与NH4SCN和水的多组分级联羟基磺化合成β-羟基硫化物。

建立了苯乙烯与NH4SCN和水的过渡-无脑多组分羟基磺化反应制β-羟基硫化物。在自由基加成2-苯基咪唑[1,2-a]吡啶后，反应机理通过多米诺骨牌反应进行。该方法具有广泛的底物范围和官能团相容性，以可接受的收率提供34种化合物。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Chemistry - An Asian Journal 化学-化学综合

CiteScore

7.00

自引率

2.40%

发文量

535

审稿时长

1.3 months

期刊介绍： Chemistry—An Asian Journal is an international high-impact journal for chemistry in its broadest sense. The journal covers all aspects of chemistry from biochemistry through organic and inorganic chemistry to physical chemistry, including interdisciplinary topics. Chemistry—An Asian Journal publishes Full Papers, Communications, and Focus Reviews. A professional editorial team headed by Dr. Theresa Kueckmann and an Editorial Board (headed by Professor Susumu Kitagawa) ensure the highest quality of the peer-review process, the contents and the production of the journal. Chemistry—An Asian Journal is published on behalf of the Asian Chemical Editorial Society (ACES), an association of numerous Asian chemical societies, and supported by the Gesellschaft Deutscher Chemiker (GDCh, German Chemical Society), ChemPubSoc Europe, and the Federation of Asian Chemical Societies (FACS).