Serum Uromodulin Is a Possible Auxiliary Diagnostic Tool for Acute Tubular Injury and Acute Interstitial Nephritis: A Case Series.

IF 0.7 Q4 UROLOGY & NEPHROLOGY

Case Reports in Nephrology and Dialysis Pub Date : 2022-09-01 DOI:10.1159/000523855

Ryosuke Usui, Tetsuya Ogawa, Chihiro Iwasaki, Kosaku Nitta, Minako Koike

引用次数: 2

Abstract

Recently, the usefulness of serum uromodulin (sUmod) as a novel renal biomarker has been attracting attention. Clinical evidence regarding sUmod measurements has been accumulated by analyzing cross-sectional data. However, little is known about the longitudinal data on sUmod. Therefore, we decided to investigate the variability of sUmod in patients with acute kidney injury due to different causes. High concentrations of sUmod have been observed in patients with acute tubular injury (ATI) and/or acute interstitial nephritis (AIN). sUmod could be used as an auxiliary diagnostic tool for ATI and AIN.

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血清尿调素可能是急性肾小管损伤和急性间质性肾炎的辅助诊断工具:一个病例系列。

近年来，血清尿调素(sUmod)作为一种新的肾脏生物标志物的应用受到了广泛的关注。通过分析横断面数据，积累了sUmod测量的临床证据。然而，人们对sUmod的纵向数据知之甚少。因此，我们决定研究sUmod在不同原因引起的急性肾损伤患者中的变异性。在急性肾小管损伤(ATI)和/或急性间质性肾炎(AIN)患者中观察到高浓度的sUmod。sUmod可作为ATI和AIN的辅助诊断工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Case Reports in Nephrology and Dialysis UROLOGY & NEPHROLOGY-

CiteScore

1.20

自引率

0.00%

发文量

审稿时长

10 weeks

期刊介绍： This peer-reviewed online-only journal publishes original case reports covering the entire spectrum of nephrology and dialysis, including genetic susceptibility, clinical presentation, diagnosis, treatment or prevention, toxicities of therapy, critical care, supportive care, quality-of-life and survival issues. The journal will also accept case reports dealing with the use of novel technologies, both in the arena of diagnosis and treatment. Supplementary material is welcomed.