Diagnostic challenge of dyspnea in the context of the COVID-19 pandemic wave: a case report.

IF 1 Q3 MEDICINE, GENERAL & INTERNAL
Zamelina Angela Razafindrasoa, Sonia Marcelle Razafimpihanina, Marie Odette Rasoafaranirina, Fidy Arnauld Martin, Finaritra Princy Parfait Andriamahenina, Diamondra Ombanjanahary Andriarimanga, Jocelyn Robert Rakotomizao, Harison Michel Tiaray, Joëlson Lovaniaina Rakotoson, Rondro Nirina Raharimanana
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Abstract

Background: Since its discovery, COVID-19 has often been the first diagnosis of dyspnea and asthenia, especially during the pandemic waves. However, it is not always COVID-19. We report a particular case of a late-diagnosed HIV-positive patient in Madagascar.

Case presentation: A 21-year-old male patient was admitted to a hospital center in Antananarivo for dyspnea and poor general condition. Physical examination revealed hypoxemia of 85% on room air. His chest X-ray showed bilateral reticular-micronodular opacities. He was suspected and treated for COVID-19. On the 15th day of hospitalization, HIV-1 infection complicated by probable pneumocystis was diagnosed. On the other hand, a multimetastatic testicular cancer was also suspected. The patient died after a few hours of hospitalization in the intensive care unit.

Conclusion: This was a case of an HIV-positive patient belatedly diagnosed in the complications stage during the COVID-19 pandemic wave. The investigation of the differential diagnoses remains crucial to avoid serial misdiagnosis and to adjust therapeutic management.

Abstract Image

COVID-19大流行背景下呼吸困难的诊断挑战:一份病例报告
背景:自发现COVID-19以来,通常首先诊断为呼吸困难和虚弱,特别是在大流行期间。然而,它并不总是COVID-19。我们报告一个特殊的情况下,一个晚期诊断艾滋病毒阳性患者在马达加斯加。病例介绍:一名21岁男性患者因呼吸困难和一般情况不佳被送入塔那那利佛一家医院中心。体检显示室内空气低氧血症达85%。胸部x线显示双侧网状微结节性混浊。他被怀疑感染COVID-19并接受了治疗。住院第15天,诊断为HIV-1感染并可能合并肺囊虫病。另一方面,多转移性睾丸癌也被怀疑。病人在重症监护室住院几小时后死亡。结论:该病例为2019冠状病毒病大流行期间晚期诊断的hiv阳性患者。鉴别诊断的研究对于避免一系列误诊和调整治疗方法至关重要。
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