An Overview of Ischemia-Reperfusion Injury: Review on Oxidative Stress and Inflammatory Response.

IF 0.9 Q3 MEDICINE, GENERAL & INTERNAL

Eurasian Journal of Medicine Pub Date : 2022-12-01 DOI:10.5152/eurasianjmed.2022.22293

Mustafa Can Güler, Ayhan Tanyeli, Fazile Nur Ekinci Akdemir, Ersen Eraslan, Saime Özbek Şebin, Derya Güzel Erdoğan, Tuncer Nacar

引用次数: 0

Abstract

Ischemia-reperfusion is a common health problem leading to several health conditions. The pathophysiology of ischemia-reperfusion is quite complex. Oxidative stress and inflammatory response contribute to ischemia-reperfusion mechanisms. Various parameters like proinflammatory cytokines, reactive oxygen species, occur during ischemia-reperfusion . There are several ways to investigate these values through biochemical and histopathologic findings. Malondialdehyde, glutathione, myeloperoxidase, superoxide dismutase, interleukin 6, interleukin 1β, tumor necrosis factor alpha, caspase-3, nuclear factor-kappa β, and LC3B (microtubu le-associated protein light chain 3, LC3) can be evaluated among these indicators.

查看原文本刊更多论文

缺血再灌注损伤概述：氧化应激和炎症反应综述

缺血再灌注是一种常见的健康问题，会导致多种健康状况。缺血再灌注的病理生理学相当复杂。氧化应激和炎症反应是造成缺血再灌注的机制之一。缺血再灌注过程中会出现各种参数，如促炎细胞因子、活性氧等。有几种方法可以通过生化和组织病理学发现来研究这些数值。在这些指标中，丙二醛、谷胱甘肽、髓过氧化物酶、超氧化物歧化酶、白细胞介素 6、白细胞介素 1β、肿瘤坏死因子 alpha、caspase-3、核因子-kappa β 和 LC3B（微管相关蛋白轻链 3，LC3）均可进行评估。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Eurasian Journal of Medicine Medicine-Medicine (all)

CiteScore

1.90

自引率

6.70%

发文量

审稿时长

16 weeks

期刊介绍： Eurasian Journal of Medicine (Eurasian J Med) is an international, scientific, open access periodical published by independent, unbiased, and triple-blinded peer-review principles. The journal is the official publication of Atatürk University School of Medicine and published triannually in February, June, and October. The publication language of the journal is English. The aim of the Eurasian Journal of Medicine is to publish original research papers of the highest scientific and clinical value in all medical fields. The Eurasian J Med also includes reviews, editorial short notes and letters to the editor that either as a comment related to recently published articles in our journal or as a case report. The target audience of the journal includes researchers, physicians and healthcare professionals who are interested or working in in all medical disciplines.