ICLAS LAQ Network for the Promotion of Animal Quality in Research.

IF 3.1 3区农林科学 Q1 VETERINARY SCIENCES

Ilar Journal Pub Date : 2021-12-31 DOI:10.1093/ilar/ilac003

Patri Vergara, Gregory Ballard, Cynthia Besch-Williford, Nobuhito Hayashimoto, Cynthia Pekow, Ana Perez, Katja Schmidt, William Shek, Martin Toft, Atsushi Yoshiki

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引用次数: 0

Abstract

ICLAS Laboratory Animal Quality Network (LAQN) programs currently consist of the Performance Evaluation Program (PEP), which focuses on microbial monitoring by and for laboratory animal diagnostic laboratories, and the Genetic Reference Monitoring Program (GENRef), which provides assay-ready reference DNA for genetic testing of mouse strains. Since 2008, PEP has grown to become a truly international program with participating laboratories in 5 continents. Launched in 2016, GENRef currently distributes DNA from 12 common inbred mouse strains for use in genetic monitoring of locally inbred colonies as well as for genetic testing of stocks, particularly genetically engineered stocks, of uncertain origins. GENRef has the capacity to include additional strains as well as additional species. PEP and GENRef provide the reagents at cost, as a resource to the international scientific community, in the interest of improving research quality in an environment of growing concern for research quality, rigor, and reproducibility.

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促进研究动物质量的LAQ网络。

ICLAS实验动物质量网络(LAQN)项目目前由性能评估项目(PEP)和遗传参考监测项目(GENRef)组成，前者侧重于实验室动物诊断实验室的微生物监测，后者为小鼠品系的基因检测提供可检测的参考DNA。自2008年以来，PEP已发展成为一个真正的国际项目，参与实验室遍布五大洲。GENRef于2016年启动，目前分发来自12种常见近亲繁殖小鼠品系的DNA，用于对当地近亲繁殖菌落进行遗传监测，以及对来源不确定的基因工程种群进行基因检测。GENRef有能力包括额外的菌株和额外的物种。PEP和GENRef以成本价提供试剂，作为国际科学界的资源，在日益关注研究质量、严谨性和可重复性的环境中提高研究质量。

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来源期刊

Ilar Journal 农林科学-兽医学

CiteScore

5.10

自引率

20.00%

发文量

审稿时长

>18 weeks

期刊介绍： The ILAR Journal is the peer-reviewed, theme-oriented publication of the Institute for Laboratory Animal Research (ILAR), which provides timely information for all who study, use, care for, and oversee the use of animals in research. The journal publishes original articles that review research on animals either as direct subjects or as surrogates for humans. According to policy, any previously unpublished animal research reported in the ILAR Journal will have been conducted according to the scientific, technical, and humanely appropriate guidelines current at the time the research was conducted in accordance with the Guide for the Care and Use of Laboratory Animals or other guidance provided by taxonomically-oriented professional societies (e.g., American Society of Mammalogy) as referenced in the Guide.