Special issue on "Novel neuropsychological instruments for the prodromal and preclinical diagnosis of Alzheimer's disease".

IF 2.6 3区 心理学 Q3 NEUROSCIENCES
Neuropsychology Pub Date : 2023-09-01 DOI:10.1037/neu0000907
Giovanni Augusto Carlesimo, Maria Stefania De Simone
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引用次数: 0

Abstract

Dementia is one of the most challenging health and social emergencies today. It affects more than 55 million people worldwide with epidemiological projections of reaching 140 million people in 2050. Diagnosis of Alzheimer's disease (AD), the clinical-pathological entity responsible for 60%-70% of all dementia cases, rests currently on the demonstration of cerebrospinal fluid or neuroimaging biomarkers, as a proxy of AD cortical neuropathology. In this context, the role of neuropsychological assessment, as a rapid and noninvasive tool able to accurately detect the early cognitive alterations and eventually promote the search for specific biological markers of AD, has become a matter of intense investigation and theoretical debate. This special issue includes original studies as well as literature reviews of the most current and promising approaches aimed at addressing the critical question of distinguishing cognitive decline due to preclinical or prodromal AD from decline associated with physiological aging. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

特刊“用于阿尔茨海默病前驱和临床前诊断的新型神经心理学仪器”。
痴呆症是当今最具挑战性的卫生和社会紧急情况之一。它影响全世界5500多万人,流行病学预测到2050年将达到1.4亿人。阿尔茨海默病(Alzheimer's disease, AD)是导致60%-70%痴呆病例的临床病理实体,其诊断目前依赖于脑脊液或神经成像生物标志物的证明,作为AD皮质神经病理学的代表。在这种背景下,神经心理学评估作为一种快速、无创的工具,能够准确地检测早期认知改变,并最终促进对阿尔茨海默病特异性生物标志物的研究,已经成为一个激烈的研究和理论争论的问题。这期特刊包括原始研究以及最新和有前途的方法的文献综述,旨在解决区分临床前或前驱AD引起的认知衰退与生理衰老相关的认知衰退的关键问题。(PsycInfo数据库记录(c) 2023 APA,版权所有)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Neuropsychology
Neuropsychology 医学-神经科学
CiteScore
4.10
自引率
4.20%
发文量
132
审稿时长
6-12 weeks
期刊介绍: Neuropsychology publishes original, empirical research; systematic reviews and meta-analyses; and theoretical articles on the relation between brain and human cognitive, emotional, and behavioral function.
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