Home Care and the Effects of Hypericum tetrapterum Oil Extract in the Treatment of Chronic Wounds During the COVID-19 Pandemic.

Elizabeta Markoska, Nikola Gramatnikovski, Iskra Pechijareva-Sadikarijo, Svetlana Krstevska-Blazhevska, Vlado Matevski
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Abstract

The COVID-19 pandemic and the need for social distancing brought about sudden changes in the health system and treatment strategies. Patients with chronic wounds were affected by these changes and had limited access to professional treatment in hospitals. They were at a higher risk of infection with COVID-19 due to comorbidities and advanced age. The aim of the study was to develop an appropriate protocol for the in-home treatment of chronic wounds due to the COVID-19 pandemic when access to hospitals is limited and the risk of infection for these patients is high. In our case, Hypericum tetrapterum oil extract was applied for four months on a volunteer, a 78-year-old male patient with a chronic wound, additionally infected with Pseudomonas aeruginosa and comorbidities. His healing status was monitored by measuring the wound size and microbiological analysis at certain intervals. The scab of wound DPHR2 (right lower leg chronic wound 2), with its diameters of d1 (40 mm) and d2 (20 mm), fell off after 22 days of the first Hypericum tetrapterum oil extract application. The scab of wound DPHR1 (right lower leg chronic wound 1), with its diameters of d1 (74 mm) and d2 (35 mm), fell off after two and a half months of treatment with Hypericum tetrapterum oil extract. The results of our study indicated that Hypericum tetrapterum oil extract has a significant wound-healing potential and might be used as traditional medicine in the treatment of chronic wounds.

COVID-19大流行期间家庭护理及四合金丝桃油提取物治疗慢性伤口的效果
COVID-19大流行和保持社交距离的必要性导致卫生系统和治疗策略发生了突然变化。慢性伤口患者受到这些变化的影响,在医院接受专业治疗的机会有限。由于合并症和高龄,他们感染COVID-19的风险更高。该研究的目的是为COVID-19大流行造成的慢性伤口制定适当的家庭治疗方案,因为这些患者去医院的机会有限,感染风险很高。在我们的案例中,我们对一位78岁的男性志愿者应用了四个月的金丝桃油提取物,该患者患有慢性伤口,另外感染了铜绿假单胞菌并伴有合并症。在一定的时间间隔内,通过测量伤口大小和微生物分析来监测患者的愈合情况。伤口DPHR2(右小腿慢性伤口2),直径分别为d1 (40 mm)和d2 (20 mm),第一次应用四贼藿油提取物22天后痂脱落。伤口DPHR1(右小腿慢性伤口1),直径分别为d1 (74 mm)和d2 (35 mm),经四合金丝桃油提取物治疗2个半月后结痂脱落。本研究结果表明,金丝桃油提取物具有显著的创面愈合潜力,可作为传统药物用于慢性创面的治疗。
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