Preconception health optimization in women with polycystic ovary syndrome - how to find the time?

IF 2.6 3区医学 Q3 ENDOCRINOLOGY & METABOLISM

Current Opinion in Endocrinology & Diabetes and Obesity Pub Date : 2022-12-01 DOI:10.1097/MED.0000000000000781

Clare Lennon, Kathryn Voss, Wendy S Vitek

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引用次数: 2

Abstract

Purpose of review: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among reproductive-age women, the most common cause of infertility among women and a major contributor to pregnancy complications.

Recent findings: Diagnostic and associated features of PCOS, including hyperandrogenism, insulin resistance, and obesity, contribute to the 2-4-fold increased risk of pregnancy-induced hypertension and preeclampsia, gestational diabetes and preterm birth observed among pregnant women with PCOS. PCOS should be diagnosed according to the 2018 International Guideline. Screening for and optimizing management of hypertension, impaired glucose tolerance and obesity in the preconception window in women with PCOS provides an opportunity to increase the odds of a spontaneous pregnancy, live birth with fertility treatment and possibly reduce the risk of pregnancy complications.

Summary: Providers should prioritize individualizing recommendations for preconception health optimization in women with PCOS in order to maximize the chance of conception, a healthy pregnancy and the health of future generations.

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多囊卵巢综合征女性孕前健康优化——如何找到时机?

综述目的:多囊卵巢综合征(PCOS)是育龄妇女中最常见的内分泌紊乱，是妇女不孕的最常见原因，也是妊娠并发症的主要原因。最近的研究发现:多囊卵巢综合征的诊断和相关特征，包括高雄激素，胰岛素抵抗和肥胖，导致妊娠高血压和子痫前期，妊娠糖尿病和早产的风险增加2-4倍。多囊卵巢综合征的诊断应根据2018年国际指南。在多囊卵巢综合征(PCOS)妇女孕前筛查和优化高血压、糖耐量受损和肥胖的管理，为增加自然妊娠、活产和生育治疗的几率提供了机会，并可能降低妊娠并发症的风险。摘要:为了最大限度地提高受孕机会、健康妊娠和后代的健康，医疗服务提供者应优先考虑对多囊卵巢综合征妇女孕前健康优化的个性化建议。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Opinion in Endocrinology & Diabetes and Obesity ENDOCRINOLOGY & METABOLISM-

CiteScore

5.80

自引率

3.10%

发文量

128

审稿时长

6-12 weeks

期刊介绍： Current Opinion in Endocrinology, Diabetes and Obesity delivers a broad-based perspective on the most recent and exciting developments in the field from across the world. Published bimonthly and featuring twelve key topics – including androgens, gastrointestinal hormones, diabetes and the endocrine pancreas, and neuroendocrinology – the journal’s renowned team of guest editors ensure a balanced, expert assessment of the recently published literature in each respective field with insightful editorials and on-the-mark invited reviews.