European Association of Urology Guidelines on Penile Size Abnormalities and Dysmorphophobia: Summary of the 2023 Guidelines

IF 5.4 3区 材料科学 Q2 CHEMISTRY, PHYSICAL
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Abstract

Context

Recommendations regarding the management of penile size abnormalities and dysmorphophobia are important in guiding evidence-based clinical practice.

Objective

To present a summary of the 2023 European Association of Urology sexual and reproductive health evidence-based recommendations for the management of penile size abnormalities and dysmorphophobia.

Evidence acquisition

A broad and comprehensive scoping exercise covering all areas of the guidelines was performed. Databases searched included Medline, EMBASE, and the Cochrane Libraries. A level of evidence and a strength of recommendation were assigned for each recommendation according to the evidence identified. The evidence cutoff date for the 2023 guidelines is June 1, 2022.

Evidence synthesis

Well-structured studies reporting high level of evidence, with standardized PROMS were deficient on penile size abnormalities and dysmorphohobia. A shared definition for short penis/micropenis was also lacking. Categorisation of penile abnormalities according to congenital, acquired, and dysmorphophobic aetiology is deemed compulsory. A detailed medical and psychosexual history and precise measurements of penile size are essential in the diagnostic pathway. Patients with normal penile size who are seeking penile augmentation should be referred for psychological evaluation for potential dysmorphophobic disorders. Penile length and girth enhancements can be achieved via a multitude of treatments, but a personalised management plan is crucial for satisfactory results. Endocrinological therapies, when indicated, are effective in the prepubertal setting only. Vacuum therapy has a limited evidence base in treatment protocols, although acceptable outcomes have been reported for penile traction therapy. Surgical techniques to enhance penile length and girth have limited evidence and should only be proposed after extensive patient counselling.

Conclusions

Management of penile abnormalities and dysmorphophobia is a complex issue with considerable ethical concerns. The adoption of a structured diagnostic and therapeutic pathway is crucial, as recommended in the guidelines.

Patient summary

Requests for medical/surgical treatments to increase penis size have increased dramatically worldwide. Several conservative and surgical treatments are available. However, few patients receive clear information on the benefits and possible harms of these treatments. These guidelines aim to provide a structured path to guide both physicians and patients in the selection of appropriate treatment(s) to increase penis size.

欧洲泌尿学协会阴茎大小异常和畸形恐惧症指南:2023 年指南摘要
背景有关阴茎大小异常和畸形恐惧症治疗的建议对于指导循证临床实践非常重要。目的对 2023 年欧洲泌尿外科协会性与生殖健康循证建议中有关阴茎大小异常和畸形恐惧症治疗的建议进行总结。证据获取进行了广泛而全面的范围界定工作,涵盖了指南的所有领域。检索的数据库包括 Medline、EMBASE 和 Cochrane 图书馆。根据已确定的证据,为每条建议指定了证据等级和推荐强度。2023 年指南的证据截止日期为 2022 年 6 月 1 日。证据综述在阴茎大小异常和畸形恐惧症方面,缺乏报告证据级别高、采用标准化 PROMS 的结构合理的研究。阴茎短小/小阴茎也缺乏共同的定义。阴茎异常必须按照先天性、后天性和畸形恐惧症病因进行分类。在诊断过程中,详细的病史和性心理史以及阴茎尺寸的精确测量至关重要。阴茎大小正常但想进行阴茎增粗手术的患者应接受心理评估,以确定是否存在潜在的畸形恐惧症。阴茎长度和周长的增加可以通过多种治疗方法来实现,但个性化的管理方案对取得满意的效果至关重要。内分泌疗法仅在青春期前有效。真空疗法在治疗方案中的证据基础有限,不过有报道称阴茎牵引疗法的效果可以接受。增加阴茎长度和周长的外科技术证据有限,只有在对患者进行广泛咨询后才可建议采用。正如指南中建议的那样,采用结构化诊断和治疗途径至关重要。患者摘要全球范围内,通过药物/手术治疗来增大阴茎的需求急剧增加。目前有多种保守治疗和手术治疗方法。然而,很少有患者能清楚地了解这些治疗方法的益处和可能的危害。本指南旨在为医生和患者提供一个结构化的途径,指导他们选择适当的治疗方法来增大阴茎。
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来源期刊
ACS Applied Energy Materials
ACS Applied Energy Materials Materials Science-Materials Chemistry
CiteScore
10.30
自引率
6.20%
发文量
1368
期刊介绍: ACS Applied Energy Materials is an interdisciplinary journal publishing original research covering all aspects of materials, engineering, chemistry, physics and biology relevant to energy conversion and storage. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrate knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important energy applications.
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