The high burden of pediatric cystic echinococcosis in Kazakhstan: epidemiological and clinical consequences.

IF 1.9 4区医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2023-12-04 DOI:10.1093/trstmh/trad065

Gaukhar Doszhanova, Agnese Colpani, Amangul Duisenova, Andrea De Vito, Zhamilya Zholdybay, Konrad Juszkiewicz, Enrico Brunetti, Adyl Katarbayev, Shokan Kaniyev, Zhanar Zhakenova, Tommaso Manciulli, Aigerim Mustapayeva

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引用次数: 0

Abstract

Background: Cystic echinococcosis (CE) is attributable to Echinococcus granulosus metacestodes. Ultrasound examinations enable a stage-specific approach to CE management. However, this approach is not often applied in endemic areas, which include Kazakhstan.

Methods: We collected clinical and ultrasound data on CE pediatric patients seen at a national referral surgical center in Almaty, Kazakhstan, during 2015-2020.

Results: We included 49 patients, and 79 cysts that were all surgically treated. All but one patient carried active cysts (CE1-CE3 stages). Twenty-six (53.2%) did not receive albendazole postsurgery. Children with CE1 and CE3a cysts underwent surgery, while the use of albendazole and percutaneous drainage were advised upon by experts.

Conclusions: A stage-specific approach to CE management in Kazakhstan is urgent, especially in the pediatric population. The rate of active cysts suggests continuing transmission of CE.

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哈萨克斯坦儿童囊性包虫病的高负担:流行病学和临床后果

背景:囊性棘球蚴病(CE)是由囊性棘球蚴所致。超声检查使CE管理的阶段特异性方法成为可能。然而，在包括哈萨克斯坦在内的流行地区并不经常采用这种方法。方法:我们收集2015-2020年期间在哈萨克斯坦阿拉木图国家转诊外科中心就诊的CE儿科患者的临床和超声数据。结果:我们纳入49例患者，79例囊肿均行手术治疗。除1例患者外，其余患者均伴有活动性囊肿(CE1-CE3期)。术后未使用阿苯达唑26例(53.2%)。CE1和CE3a囊肿患儿接受手术治疗，专家建议使用阿苯达唑和经皮引流。结论:在哈萨克斯坦，一种针对特定阶段的CE管理方法迫在眉睫，特别是在儿科人群中。活动性囊肿的发生率提示CE的持续传播。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Transactions of The Royal Society of Tropical Medicine and Hygiene 医学-公共卫生、环境卫生与职业卫生

CiteScore

4.00

自引率

9.10%

发文量

115

审稿时长

4-8 weeks

期刊介绍： Transactions of the Royal Society of Tropical Medicine and Hygiene publishes authoritative and impactful original, peer-reviewed articles and reviews on all aspects of tropical medicine.