Clinical standardization for the detection of hemispheric dominance for steady-state auditory evoked fields in normal hearing.

IF 1.9 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL
Mao-Che Wang, Tai-Shih Chi, An-Suey Shiao, Lieber Po-Hung Li, Jen-Chuen Hsieh
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引用次数: 0

Abstract

Background: Steady-state auditory evoked responses (SSAERs) are promising indicators of major auditory function. The improvement in accessibility in the clinical setting depends on the standardization and definition of the characteristics of SSAERs. There have been some insights into the changes in the interhemispheric dominance of SSAERs in some clinical entities. However, the hemispheric asymmetry of SSAERs in healthy controls remains inconclusive.

Methods: Twelve right-handed healthy volunteers with normal hearing were recruited. Steady-state auditory evoked fields (SSAEFs) were measured binaurally using magnetoencephalography (MEG) under pure-tone auditory stimuli at 1000 Hz with an amplitude modulation frequency of 43 Hz. The laterality index, based on the ratio of SSAEF strength over the right hemisphere to that over the left hemisphere, was also analyzed.

Results: The SSAEFs source was localized bilaterally on the superior temporal plane, with an orientation centripetal to the auditory cortex. The laterality index ranged from 1.1 to 2.3, and there were no sex differences. In all subjects, the strength of the SSAEFs was significantly weaker in the left hemisphere than in the right hemisphere ( p = 0.014).

Conclusion: Right-sided dominance of the SSAEFs was verified in subjects with normal hearing. Acoustic sources clinically available in audiometric tests were used as stimuli. Such a simplification of parameters would be helpful for the standardization of precise production and the definition of the characteristics of SSAERs. Because MEG is still not easily accessible clinically, further studies using electroencephalography with larger sample sizes are necessary to address these issues.

正常听力稳态听觉诱发场半球优势检测的临床标准化。
背景:稳态听觉诱发反应(SSAER)是一种很有前途的主要听觉功能指标。临床环境中可及性的改善取决于SSAER特征的标准化和定义。对某些临床实体中SSAER半球间优势的变化已有一些见解。然而,健康对照组SSAER的半球不对称性仍然没有定论。方法:招募12名听力正常的右手健康志愿者。稳态听觉诱发场(SSAEF)是使用脑磁图(MEG)在1000Hz的纯音听觉刺激下以43Hz的调幅频率进行双耳测量的。还分析了基于右半球SSAEF强度与左半球SSAEF力量之比的偏侧性指数。结果:SSAEFs源位于双侧颞上平面,方向向听觉皮层向心。偏侧性指数在1.1到2.3之间,没有性别差异。在所有受试者中,左半球SSAEF的强度明显弱于右半球(p=0.014)。结论:听力正常的受试者证实了SSAEF的右侧优势。听力测试中临床可用的声源被用作刺激。参数的这种简化将有助于精确生产的标准化和SSAER特性的定义。由于MEG在临床上仍然不容易获得,因此有必要使用更大样本量的脑电图进行进一步研究来解决这些问题。
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来源期刊
Journal of the Chinese Medical Association
Journal of the Chinese Medical Association MEDICINE, GENERAL & INTERNAL-
CiteScore
6.20
自引率
13.30%
发文量
320
审稿时长
15.5 weeks
期刊介绍: Journal of the Chinese Medical Association, previously known as the Chinese Medical Journal (Taipei), has a long history of publishing scientific papers and has continuously made substantial contribution in the understanding and progress of a broad range of biomedical sciences. It is published monthly by Wolters Kluwer Health and indexed in Science Citation Index Expanded (SCIE), MEDLINE®, Index Medicus, EMBASE, CAB Abstracts, Sociedad Iberoamericana de Informacion Cientifica (SIIC) Data Bases, ScienceDirect, Scopus and Global Health. JCMA is the official and open access journal of the Chinese Medical Association, Taipei, Taiwan, Republic of China and is an international forum for scholarly reports in medicine, surgery, dentistry and basic research in biomedical science. As a vehicle of communication and education among physicians and scientists, the journal is open to the use of diverse methodological approaches. Reports of professional practice will need to demonstrate academic robustness and scientific rigor. Outstanding scholars are invited to give their update reviews on the perspectives of the evidence-based science in the related research field. Article types accepted include review articles, original articles, case reports, brief communications and letters to the editor
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