Translumbar type II endoleak embolization with a new liquid iodinated polyvinyl alcohol polymer: Case series and review of current literature.

Giovanni Leati, Francesco Di Bartolomeo, Gabriele Maffi, Luca Boccalon, Domenico Diaco, Edoardo Segalini, Angelo Spinazzola
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Abstract

Purpose: To describe our experience with the use of a novel iodized Polyvinyl Alcohol Polymer liquid agent (Easyx) in type II endoleak treatment with translumbar approach.

Methods: Our case series is a retrospective review of patients with type II endoleak (T2E) treated with Easyx from December 2017 to December 2020. Indication for treatment was a persistent T2E with an increasing aneurysm sac ≥5 mm on computed tomography angiography (CTA) over a 6-month interval. Technical success was defined as the embolization of the endoleak nidus with reduction or elimination of the T2E on sequent CTA evaluation. Clinical success was defined as an unchanged or decreased aneurysm sac on follow-up CTA. Secondary endpoints included the presence of artifacts in the postprocedural cross-sectional tomographic imaging and post and intraprocedural complications.

Results: Ten patients were included in our retrospective analysis. All T2E were successfully embolized. Clinical success was achieved in 9 out of 10 patients (90%). The mean follow-up was 14 3-20 months. No beam hardening artifact was observed in follow-up CT providing unaltered imaging.

Conclusion: Easyx is a novel liquid embolic agent with lava-like characteristics and unaltered visibility on subsequent CT examinations. In our initial experience, Easyx showed to have all the efficacy requisites to be an embolization agent for type II EL management. Its efficacy, however, should be evaluated in more extensive studies and eventually compared with other agents.

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一种新型液体碘化聚乙烯醇聚合物经腰椎II型内漏栓塞术:病例系列和当前文献综述。
目的:描述我们使用一种新型碘化聚乙烯醇聚合物液体剂(Easyx)经腰椎入路治疗II型内漏的经验。方法:我们的病例系列是对2017年12月至2020年12月接受Easyx治疗的II型endoleak (T2E)患者的回顾性分析。治疗的适应症是持续的T2E,在计算机断层血管造影(CTA)上动脉瘤囊增加≥5mm,间隔6个月。技术上的成功被定义为栓塞内漏病灶并在随后的CTA评估中减少或消除T2E。临床成功的定义是在随访的CTA上动脉瘤囊没有改变或减小。次要终点包括术后断层断层成像中的伪影以及术后和术中并发症。结果:10例患者纳入回顾性分析。所有T2E均成功栓塞。10例患者中有9例(90%)取得临床成功。平均随访14 ~ 20个月。随访CT未见光束硬化伪影,影像学未见改变。结论:Easyx是一种新型的液体栓塞剂,具有类似熔岩的特征,在随后的CT检查中可见性不变。在我们的初步经验中,Easyx显示出作为II型EL治疗的栓塞剂所必需的所有疗效。然而,它的疗效应该在更广泛的研究中进行评估,并最终与其他药物进行比较。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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