Efficacy and safety of cardiac resynchronization therapy in chemotherapy-induced cardiomyopathy: A systematic review

IF 1.1 4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS
Muhammad Shehram MBBS, Hiba Khalid MBBS, Hafiz Muhammad Shafique MBBS, Bakht Umer MBBS, Awais Zafar MBBS, Asif Ullah MBBS, Syed Muhammad Jawad Zaidi MBBS, Jawad Basit MBBS, Amin Mehmoodi MD, Jahanzeb Malik MBBS
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引用次数: 0

Abstract

Objective

The aim of the study was to assess the efficacy of cardiac resynchronization therapy (CRT) in patients with chemotherapy-induced cardiomyopathy (CIC).

Methods

With the increasing incidence of CIC, the association of CRT with improvement in clinical outcomes, echocardiographic parameters, and New York Heart Classification (NYHA) class was assessed through this qualitative systematic review.

Results

The five studies included a total of 169 patients who underwent CRT after CIC, and of these, 61 (36.1%) patients were males. All studies showed an improvement in left ventricular ejection fraction (LVEF), among other echocardiographic parameters of LV volume. However, these findings are limited by short follow-up periods, small sample sizes, and the absence of a control group.

Conclusion

CRT was associated with improvement in all patient parameters with CIC.

Abstract Image

心脏再同步化治疗在化疗引起的心肌病中的疗效和安全性:一项系统综述
目的评价心脏再同步化治疗(CRT)对化疗性心肌病(CIC)患者的疗效。方法随着CIC发生率的增加,通过定性系统评价CRT与临床结局、超声心动图参数和纽约心脏分级(NYHA)改善的关系。结果5项研究共纳入169例CIC术后行CRT的患者,其中男性61例(36.1%)。所有研究均显示左心室射血分数(LVEF)以及左室容积的其他超声心动图参数有所改善。然而,这些发现受到随访时间短、样本量小以及缺乏对照组的限制。结论CRT与CIC患者各项参数的改善相关。
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来源期刊
CiteScore
3.40
自引率
0.00%
发文量
88
审稿时长
6-12 weeks
期刊介绍: The ANNALS OF NONINVASIVE ELECTROCARDIOLOGY (A.N.E) is an online only journal that incorporates ongoing advances in the clinical application and technology of traditional and new ECG-based techniques in the diagnosis and treatment of cardiac patients. ANE is the first journal in an evolving subspecialty that incorporates ongoing advances in the clinical application and technology of traditional and new ECG-based techniques in the diagnosis and treatment of cardiac patients. The publication includes topics related to 12-lead, exercise and high-resolution electrocardiography, arrhythmias, ischemia, repolarization phenomena, heart rate variability, circadian rhythms, bioengineering technology, signal-averaged ECGs, T-wave alternans and automatic external defibrillation. ANE publishes peer-reviewed articles of interest to clinicians and researchers in the field of noninvasive electrocardiology. Original research, clinical studies, state-of-the-art reviews, case reports, technical notes, and letters to the editors will be published to meet future demands in this field.
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