Short Cycle, Intermittent Therapy: A Valuable Option in Selected, Virologically Suppressed People Living with HIV.

IF 1.5 4区医学 Q4 IMMUNOLOGY

AIDS research and human retroviruses Pub Date : 2024-02-01 Epub Date: 2023-08-31 DOI:10.1089/AID.2022.0168

Massimiliano Lanzafame, Emanuela Lattuada, Dora Luise, Andrea Delama, Daniela Fait, Sandro Vento

引用次数: 0

Abstract

The use of long-acting antiretroviral regimens will not be suitable for all people living with HIV for various reasons (previous virological failure with drugs of the same class, side effects, logistic difficulties, and costs). We think that short-cycle therapies could represent a feasible and valuable option for antiretroviral treatment optimization in selected individuals. So here we review clinical evidence about efficacy of short-cycle therapy in suppressed HIV-infected patients.

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短周期间歇疗法：短周期、间歇性疗法：对部分病毒抑制的艾滋病病毒感染者而言是一种宝贵的选择。

由于种种原因（先前使用同类药物的病毒学治疗失败、副作用、后勤困难和费用），长效抗逆转录病毒疗法并不适合所有艾滋病毒感染者。我们认为，短周期疗法可以作为优化抗逆转录病毒疗法的一种可行且有价值的选择，适用于特定人群。因此，我们在此回顾了有关短周期疗法在艾滋病病毒感染者中疗效的临床证据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

AIDS research and human retroviruses 医学-病毒学

CiteScore

3.10

自引率

6.70%

发文量

201

审稿时长

3-6 weeks

期刊介绍： AIDS Research and Human Retroviruses was the very first AIDS publication in the field over 30 years ago, and today it is still the critical resource advancing research in retroviruses, including AIDS. The Journal provides the broadest coverage from molecular biology to clinical studies and outcomes research, focusing on developments in prevention science, novel therapeutics, and immune-restorative approaches. Cutting-edge papers on the latest progress and research advances through clinical trials and examination of targeted antiretroviral agents lead to improvements in translational medicine for optimal treatment outcomes. AIDS Research and Human Retroviruses coverage includes: HIV cure research HIV prevention science - Vaccine research - Systemic and Topical PreP Molecular and cell biology of HIV and SIV Developments in HIV pathogenesis and comorbidities Molecular biology, immunology, and epidemiology of HTLV Pharmacology of HIV therapy Social and behavioral science Rapid publication of emerging sequence information.