Selected environmental factors in mothers of newborns subjected to the therapeutic hypothermia - a case control study.

IF 1.4 4区医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

International journal of occupational medicine and environmental health Pub Date : 2023-03-02 DOI:10.13075/ijomeh.1896.01953

Edyta Barnaś, Iryna Basiuha, Elżbieta Porada, Marek Sobolewski, Joanna Skręt-Magierło, Lyudmyla Pakharenko

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引用次数: 0

Abstract

Objectives: Hypothermia is an established method of treating severe forms of perinatal hypoxia in newborns. Some of them develop neonatal encephalopathy, which is associated with high morbidity and mortality. Therefore, prophylaxis of this pathology is important as well as determining environmental factors in mothers of newborns affected by this pathology. The aim of the study was to assess of selected environmental factors in mothers of newborns qualified for hypothermia.

Material and methods: The material consisted of 102 subjects, including 51 mothers of newborns with hypoxic-ischemic encephalopathy referred for hypothermia treatment (group I) and 51 mothers of newborns without signs of hypoxia (group II). The case-control study was carried out in the third level reference centre. It is 1 of 20 centers of therapeutic hypothermia for newborn in Poland. Data was collected based on a data collection sheet. Study groups were compared in terms of demographic and environmental data. The odds ratio (OR) was determined and the logistic regression analysis of univariate and multivariate regression was used to determine the probability of the need for hypothermia in the study group.

Results: The groups did not differ in terms of age, BMI and place of living. The need to use hypothermia increased in pregnant women living together with their parents (OR = 6.8, 95% CI: 2.4-19.6) also in case of exposure to factors at the workplace, i.e., noise (OR = 4.1, 95% CI: 1.1-15.5).

Conclusions: Based on the results of our case-control study we postulate to pay attention during preconception care to proper preparation for pregnancy especially in younger women exposed to nuisance in the work environment and at home. In this area postulated activities should include education programs, in close cooperation occupational medicine practitioners and obstetricians even before the conception as a part of pre-conception counseling. Int J Occup Med Environ Health. 2023;36(1):59-68.

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新生儿母亲接受治疗性低温治疗的环境因素-一项病例对照研究。

目的:低温治疗是治疗新生儿围产期严重缺氧的一种常用方法。他们中的一些人发展为新生儿脑病，这与高发病率和死亡率有关。因此，预防这种病理是很重要的，以及确定受这种病理影响的新生儿母亲的环境因素。该研究的目的是评估选定的环境因素，在母亲的新生儿符合低温。材料和方法:材料包括102名受试者，其中51名新生儿的母亲患有缺氧缺血性脑病，需要低温治疗(I组)，51名新生儿的母亲没有缺氧的迹象(II组)。病例对照研究在三级参考中心进行。它是波兰20个新生儿低温治疗中心之一。根据数据收集表收集数据。研究小组在人口和环境数据方面进行了比较。确定优势比(OR)，并采用单因素回归和多因素回归的logistic回归分析来确定研究组需要低温治疗的概率。结果:两组在年龄、BMI和居住地方面没有差异。与父母同住的孕妇使用低温疗法的需求增加(OR = 6.8, 95% CI: 2.4-19.6)，在暴露于工作场所因素(即噪音)的情况下(OR = 4.1, 95% CI: 1.1-15.5)。结论:根据我们的病例对照研究结果，我们假设在孕前护理中要注意适当的怀孕准备，特别是在工作环境和家庭中暴露于滋扰的年轻女性。在这一领域，假定的活动应包括教育计划，在职业医学从业者和产科医生的密切合作下，甚至在怀孕前作为孕前咨询的一部分。中华医学杂志，2009;36(1):59-68。

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来源期刊

International journal of occupational medicine and environmental health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

3.40

自引率

5.00%

发文量

审稿时长

7.5 months

期刊介绍： The Journal is dedicated to present the contemporary research in occupational and environmental health from all over the world. It publishes works concerning: occupational and environmental: medicine, epidemiology, hygiene and toxicology; work physiology and ergonomics, musculoskeletal problems; psychosocial factors at work, work-related mental problems, aging, work ability and return to work; working hours, shift work; reproductive factors and endocrine disruptors; radiation, ionizing and non-ionizing health effects; agricultural hazards; work safety and injury and occupational health service; climate change and its effects on health; omics, genetics and epigenetics in occupational and environmental health; health effects of exposure to nanoparticles and nanotechnology products; human biomarkers in occupational and environmental health, intervention studies, clinical sciences’ achievements with potential to improve occupational and environmental health.