DNA damage induces p53-independent apoptosis through ribosome stalling

已完结 10 由 27Hz. 发布于 2024/8/14 20:28:00

DOI:10.1126/science.adh7950
作者：Nicolaas J. Boon, Rafaela A. Oliveira, Pierré-René Körner, Adva Kochavi, Sander Mertens, Yuval Malka, Rhianne Voogd, Suzanne E. M. van der Horst, Maarten A. Huismans, Lidwien P. Smabers, Jonne M. Draper, Lodewyk F. A. Wessels, Peter Haahr, Jeanine M. L. Roodhart, Ton N. M. Schumacher, Hugo J. Snippert, Reuven Agami, Thijn R. Brummelkamp
文献类型：期刊论文
补充材料：只需要正文

American Association for the Advancement of Science (AAAS)

Abstract：In response to excessive DNA damage, human cells can activate p53 to induce apoptosis. Cells lacking p53 can still undergo apoptosis upon DNA damage, yet the responsible pathways are unknown

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