Iterative Design of Ionizable Lipids for Intramuscular mRNA Delivery

已完结 10 由 1236544 发布于 2024/6/13 10:44:30

DOI:10.1021/jacs.2c10670
作者：Grayson Tilstra, Julien Couture-Senécal, Yan Ming Anson Lau, Alanna M. Manning, Daniel S. M. Wong, Wanda W. Janaeska, Titobioluwa A. Wuraola, Janice Pang and Omar F. Khan*,
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：Lipid nanoparticles (LNPs) are the most clinically advanced delivery vehicles for RNA and have enabled the development of RNA-based drugs such as the mRNA COVID-19 vaccines. Functional deliv

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